Watch Online: Best Medicine (2026)

Best Medicine is the upcoming comedy-drama series that proves sometimes the best cure for a small town's problems is a brilliant surgeon with absolutely zero patience for nonsense. Premiering January 4, 2026, on FOX, this fresh take on the fish-out-of-water comedy features Josh Charles as a Boston surgeon who trades prestigious operating rooms for a cozy East Coast fishing village—and quickly discovers that healing a community is far more complicated than performing surgery.

The Story Behind Best Medicine (2026)

"Small town doctor. Big time issues."

Martin Best has it all: a thriving surgical career in Boston, accolades, and a prestigious reputation. But something's missing. So he makes a shocking decision to leave it all behind and return to the quaint East Coast fishing village where he spent idyllic summers as a child, taking on the role of the town's general practitioner.

There's just one problem: Martin's blunt demeanor and borderline rude bedside manner don't exactly endear him to the quirky, emotionally needy locals who desperately need his help. Despite being the only doctor for miles, Martin manages to alienate nearly everyone in town. What unfolds is a hilarious and heartwarming exploration of whether a small town—and one brilliant but difficult man—can find common ground.

When Does Best Medicine Premiere?

Best Medicine officially premieres on January 4, 2026 on FOX. The first season consists of 11 episodes, and the series has already been confirmed as a returning series, so there's plenty more to come.

Full Cast & Crew

Leading the ensemble cast is Josh Charles as Dr. Martin Best, joined by acclaimed actors Abigail Spencer, Josh Segarra, Cree Cicchino, and Annie Potts rounding out the supporting cast that brings the colorful town to life.

The series is created and directed by Liz Tuccillo, Ben Silverman, and Rodney Ferrell, with production handled by Propagate Content and FOX Entertainment Studios. The show hails from the United States and airs on FOX.

Genre & What to Expect

Best Medicine blends comedy and drama into a compelling character-driven narrative. With a current rating of 7.2/10, the series promises equal parts humor and heart, perfect for viewers who enjoy ensemble comedies with genuine emotional depth.

How to Watch Best Medicine Online

Streaming availability details will be announced closer to the official premiere date on January 4, 2026. Check back here regularly for the latest information on where you can watch Best Medicine online, including which streaming platforms will carry the series.

Stay Tuned for Updates

Don't miss the premiere of Best Medicine when it arrives in January 2026. Bookmark this page to stay updated on streaming availability, episode releases, and all the latest news about the series.

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